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Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) was identified as a metastatic driver CEACAM5 overproduction enriched for an epithelial gene expression pattern and facilitated tumor outgrowth at metastatic sites Tissues from patients with metastatic breast cancer confirmed elevated levels of CEACAM5 in lung metastases relative to breast tumors and an inverse correlation between CEACAM5 and the mesenchymal marker vimentin was demonstrated
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Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
The Zymo-Spin IIN features durable polypropylene construction and contains a unique silica-based matrix that allows purification of up to 25 g of DNA, and 50 g of RNA, in 25 l eluate. Capacity is 900 l.
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
Small and Specialty Supplier Partner Small and/or specialty supplier based on Federal laws and SBA requirements. Learn More
ProtoGel (30%); National Diagnostics; 37.5:1 acrylamide to bisacrylamide stabilized soln.; Optimized for SDS-PAGE of proteins (Laemmli gels); Consistently crystal clear gels, zero fluorescence; Stabilized for long shelf life; Size: 1L
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More
The receptors CD96 and TIGIT are expressed on the surface of T and natural killer (NK) cells and recent studies suggest both play important inhibitory roles in immune function CD96 has been shown to modulate immune cell activity in mice with Cd96-/- mice displaying hypersensitive NK-cell responses to immune challenge and significant tumor resistance The counterbalance between the putative inhibitory CD96 and TIGIT receptors and the activating receptor CD226 offers unique strategies for immuno-oncology drug development
Encompass Procurement Services Non-distribution item offered as a customer accommodation; additional freight charges may apply. Learn More